I wanted to add some pep to an old ESXi 5.5 system by installing an SSD. I picked up a Samsung 1TB QVO SSD on a deal and was excited to get it installed. After it was installed, I went through the process of moving VMs from the old drive to the SSD. Booted up some Linux VMs and they seemed to run perfectly. When I got to a Windows VM, the Windows system become unresponsive. Looking at the performance of the VM in VSphere, the latency was extremely high. I did not keep any screenshots of the highest peaks, but it was hitting in the hundreds of thousands. Abysmal.
I tried researching the behavior but came up short. I tried installing a fresh Windows VM thinking this one was corrupt, no improvement. In the end, I purchased a Samsung 1TB EVO, cloned the QVO to the EVO, installed and ran the same Windows VM that was performing poorly on the QVO, and it ran perfectly. Booted up a bunch of VMs to try and impact performance but it was 100x times better than the QVO. I ended up throwing the QVO into a laptop (running Windows) and it runs perfectly. I don't know if this was due to the QVO having issues with handling larger files or something else.
tl/dr; The Samsung QVO drive performed poorly (for Windows VMs) on ESXi 5.5 - Replaced with an EVO and no more issues.